Understanding CBDV benefits is necessary to make the best possible use of this little-known but powerful cannabinoid. CBDV is the rarer, non-intoxicating cousin of the well-known cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD).
Research suggests that CBDV may be beneficial for reducing nausea. Its action on the endocannabinoid system is thought to be more effective than other antinausea cannabinoids.
In patients with epilepsy, CBDV has been found to reduce seizures. It is due to its ability to reduce the activity of TRP channels in neurons, resulting in reduced excitability.
In addition, CBDV can dampen seizures by stimulating GABA and glutamate levels in the brain. CBDV benefits people with autism since alterations in these neurotransmitters have been linked to specific symptoms.
CBDV is a “varin” variant of the cannabinoid cannabis sativa (CBD). This variant has been shown to help with anxiety, inflammation, nausea, and neurological conditions.
Researchers have found that a single acute dose of CBDV shifts subcortical levels of Glx, the brain’s primary excitatory neurotransmitter. Interestingly, it also shifts the production of GABA+ in BG and DMPFC, which can be helpful for psychiatric disorders like autism spectrum disorder.
Lastly, CBDV has the potential to aid with repeated behavioral and communication issues, inhibit chemically-induced seizures, increase myotube (muscle fiber) formation, reduce inflammation, and may help with Rett syndrome. These advantages appear encouraging, even though research is still in its infancy.
Inflammation is a critical process your body uses to deal with injury and infection. Unfortunately, it also plays a significant role in many diseases.
CBDV can reduce inflammation by activating transient receptor potential ankyrin (TRPA1) and opening the mitochondrial permeability transition pore (mPTP). It reduces intracellular calcium levels, decreases cell viability, and decreases the production of pro-inflammatory mediators such as IL-6/IL-8/MMP-3.
Enhances Muscle Function
Exercise, especially high-intensity ones, can cause microscopic damage to muscle fibers that trigger your body to respond and repair. It can result in muscle soreness or stiffness that you may not be able to shake off for a few days.
CBDV can reduce this muscle soreness by reducing inflammation and promoting better muscle function. It can also enhance skeletal muscle function, which is helpful for people who suffer from conditions such as Duchenne muscular dystrophy.
Treats Rett Syndrome
CBDV is a natural product that can help treat Rett Syndrome. This condition is caused by a rare gene mutation leading to severe speech and muscle coordination impairments.
Treats Multiple Sclerosis
Spasticity is among the most common and often poorly controlled symptoms of multiple sclerosis (MS). It can seriously impact the patient’s quality of life, and many patients cannot cope with it effectively.
Several medications are available to help alleviate spasticity in MS. These include tizanidine and baclofen, which relax muscles. However, these drugs can cause unpleasant side effects like peptic ulcers, mood swings, and increased blood pressure.
A neurological condition known as epilepsy is brought on by aberrant brain neuronal cell activity. It can affect your quality of life, cause a loss of motor and sensory abilities, and can be fatal.